Előadás a BME Kognitív Tudományi Központ házi kollokvium sorozata keretében: Előadó: Anette Karmiloff-Smith (Institute of Child Health, London Neurocognitive Development Unit) Cím: Five ways of exploring genotype/phenotype relations: a cognitive developmental perspective. Absztrakt: In this talk I will discuss 5 ways in which to explore genotype/phenotype relations. I will take Williams syndrome (WS) as my model disorder but argue that the neuroconstructivist approach applies equally to other genetic disorders. The 5 approaches involve: computational models of deficits introduced in the start state vs the end state; the more creative and developmental use of animal models; patients with genetic deletions similar to WS but with seemingly normal cognitive phenotypes; the differentiation of the behavioural vs cognitive phenotype when scores fall within the normal range; and the importance of focusing on the infant start state. I conclude by stressing how low-level impairments in early development have a cascading effect on the higher-level cognitive outcome. Idő: 2003. december 18. csütörtök, du 4-6 Hely: BME Oktatói Klub, K épület I. emelet 66. Minden érdeklődőt szeretettel várunk. Jakab Zoltán