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Képalkotó Központ által szervezett alábbi előadásra:
Alpha Closed-Loop Auditory Stimulation: Mechanistic investigations and
application to sleep onset and memory retention.
Henry Hebron, Ph.D.
Sleep and Dreams Lab, Netherlands Institute for Neuroscience, Amsterdam,
The Netherlands
School of Psychology, University of Surrey, United Kingdom
Surrey Sleep Research Section, University of Surrey, United Kingdom
Az előadás időpontja:
2026. január 30. 11:00 óra
Az előadás helyszíne:
HUN-REN TTK földszinti kis konferenciaterme
1117 Budapest, Magyar tudósok körútja 2.
Abstract: Alpha oscillations play a vital role in managing the brain’s
resources and inhibiting neural activity, as a function of their phase
and amplitude, and are changed in many brain disorders. Developing
explicit models for the modulation of alpha rhythms by external means
(e.g., sound) is therefore integral if we are to develop focused
interventions. Here, across four independent experiments, I demonstrate
that alpha oscillations respond to sound in a phase-dependent manner,
and introduce Alpha Closed-Loop Auditory Stimulation (αCLAS) as an
EEG-based method to modulate and investigate these brain rhythms in
humans with specificity and selectivity, using phase-targeted auditory
stimulation. In addition to my mechanistic investigations, I also show
the functional application of αCLAS to sleep onset and memory
retention.There remains much to be explored, regarding the application
of αCLAS to neural oscillation-dependent behaviours, but I contend that
sound can provide more utility in this context than previously
considered, particularly if stimulation is used to address the brain on
its own terms, through closed-loop approaches.
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