The CEU Department of Cognitive Science cordially invites you to a talk
(as part of its Departmental Colloquium series)
by
Zoltan Nadasdy
Seton Brain & Spine Institute, Dept. of Psychology, UT Austin,
Dept. of Cognitive Psychology, ELTE Budapest
Date: Wednesday, Oct 3, 2012 - 17:00 - 18:30
Location: Department of Cognitive Science, CEU, Frankel Leó út 30-34.,
Room G15
Grid cells and phase coding in the human brain
Grid cells were discovered in the rodent brain but direct evidence for
their human analogue is still lacking. These neurons are active
whenever the animal passes equidistant spatial locations with a 60
degree rotational symmetry, making up a characteristic hexagonal
tessellation pattern. The spatially periodic activity is assumed to
serve as a scale free reference for spatial navigation. Searching for
the human analogue, we recorded single neurons from the entorhinal
cortex of epilepsy patients during spatial navigation in a virtual
reality environment. We found a broad repertoire of spatially periodic
firing patterns from each patient, including those of typical of grid
cells. In addition, we investigated the relationship of spatially
periodic activity to ongoing local field oscillations, in particular
to theta and gamma rhythms. Our preliminary data show a spatially
periodic modulation of spike phases relative to gamma oscillations,
which are consistent across multiple cells from the same patient. We
propose that a combination of firing rate and firing phase coding may
underlie spatial navigation in the human entorhinal cortex.
We're looking forward to see you there (Frankel Leo u. 30-34) !
Cognitive Science Events at CEU:
http://cognitivescience.ceu.hu/events
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