[Koglist] Gustavo Deco: "The Dynamics of Resting Fluctuations in the Brain", CEU Kognitívtudományi Tanszék, június 9.

Tisztelt Kollégák, Csak a biztonság kedvéért, az előadás a 2015. június 9-én kedden du. 5 órakor Gustavo Deco (Universitat Pompeu Fabra, Barcelona) előadást tart a CEU Kognitívtudományi Tanszékén "The Dynamics of Resting Fluctuations in the Brain" címmel. Részletek a levél alján (figyelem, a tanszék nemrég új helyre költözött). Minden érdeklődőt szeretettel várunk. Az előadó néhány publikációja a közelmúltból: Tauste Campo A, Martinez-Garcia M, Nácher V, Luna R, Romo R, Deco G. Task-driven intra- and interarea communications in primate cerebral cortex. Proc Natl Acad Sci USA 112:4761-6, 2015. Bettinardi RG, Tort-Colet N, Ruiz-Mejias M, Sanchez-Vives MV, Deco G. Gradual emergence of spontaneous correlated brain activity during fading of general anesthesia in rats: Evidences from fMRI and local field potentials. Neuroimage 114:185-98, 2015. Deco G, Kringelbach ML. Great expectations: using whole-brain computational connectomics for understanding neuropsychiatric disorders. Neuron 84:892-905, 2014. Deco G, Ponce-Alvarez A, Hagmann P, Romani GL, Mantini D, Corbetta M. How local excitation-inhibition ratio impacts the whole brain dynamics. J Neurosci 34:7886-98, 2014 Cabral J, Kringelbach ML, Deco G. Exploring the network dynamics underlying brain activity during rest. Prog Neurobiol 114:102-31, 2014. Ponce-Alvarez A, Thiele A, Albright TD, Stoner GR, Deco G. Stimulus-dependent variability and noise correlations in cortical MT neurons. Proc Natl Acad Sci USA 110:13162-7, 2013. Üdvözlettel, Lengyel Máté -- Computational and Biological Learning Lab Cambridge University Engineering Department Trumpington Street, Cambridge CB2 1PZ, UK tel: +44 (0)1223 748 532, fax: +44 (0)1223 332 662 Department of Cognitive Science Central European University Oktober 6 street 7, Budapest H-1051, Hungary tel: +36 1 887 5142 , fax: +36 1 887 5010 email: m.lengyel(a)eng.cam.ac.uk web: www.eng.cam.ac.uk/~m.lengyel *** The CEU Department of Cognitive Science cordially invites you to a talk (as part of its Departmental Colloquium series) by Gustavo Deco (Universitat Pompeu Fabra, Barcelona, Spain) Date: Tuesday, June 9, 2015 - 17:00-18:30 Location: Department of Cognitive Science, CEU, Oktober 6 street 7, room 101. The Dynamics of Resting Fluctuations in the Brain The grand average functional connectivity (FC) of a resting brain captures properly the well- structured spatial correlations between different brain areas. Whole-brain -models explicitly linking spontaneous local neuronal dynamics with the tractography based anatomical structure of the brain are able to explain the emergence of those spatial resting correlations. Nevertheless, resting activity is not only spatially structured but also shows a very stereotypical temporal structure which is characterized by rapid transitions switching between a few discrete FC states across time. In this talk, we introduce a powerful theoretical framework, which allows us to demonstrate that resting functional connectivityFC dynamics (FCD) constrains more strongly the dynamical working point of whole-brain models. Furthermore, using a very general neural mass model based on the normal form of a Hopf bifurcation we are able to demonstrate that the temporal dynamics of resting state fluctuations emerges at the edge of the transition between asynchronous to oscillatory behavior. Even more importantly, at that particular working point the global metastability of the whole brain is maximized. By optimizing the spectral characteristics of each local brain node, we discover the dynamical core of the brain, i.e. the set of nodes, which drives by oscillations the rest of the whole brain. This dynamical core can be interpreted as the “memory” core of nodes sustaining consciousness.