Below is a link to the forthcoming BBS target article
Self-Experimentation as a Source of New Ideas:
Ten Examples About Sleep, Mood, Health, and Weight
by
Seth Roberts
http://www.bbsonline.org/Preprints/Roberts/Referees/
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Self-Experimentation as a Source of New Ideas:
Ten Examples About Sleep, Mood, Health, and Weight
Seth Roberts
University of California, Berkeley
ABSTRACT: We know little about how to generate plausible new scientific
ideas. So it is noteworthy that 12 yr of self-experimentation led to the
discovery of several surprising cause-effect relationships and helped
produce a new theory. The cause-effect relationships are: (a) Seeing faces
in the morning on television decreased mood in the evening (> 10 h later)
and improved mood the next day (> 24 h later), yet had no detectable
effect before that (0-10 h later). The effect was strongest if the faces
were life-sized and at a conversational distance. Travel across time zones
reduced the effect for a few weeks. (b) Standing 8 h/day reduced early
awakening and made sleep more restorative, even though more standing was
associated with less sleep. (c) Morning light (1 h/day) reduced early
awakening and made sleep more restorative. (d) Breakfast increased early
awakening. (e) Standing and morning light together eliminated colds (upper
respiratory tract infections) for > 5 yr. (f) Drinking lots of water,
eating low-glycemic-index foods, and eating sushi each caused a modest
weight loss. (g) Drinking unflavored fructose water caused a large weight
loss, accompanied by much less hunger than usual, that has been sustained > 1
yr. Unflavored sucrose water had similar effects. The sugar-water
effect was discovered with the help of a new theory of weight control,
which assumes that flavors associated with calories raise the body-fat set
point-the stronger the association, the greater the increase. Between
meals the set point declines. Long-term self-experimentation seems to be a
good way to generate ideas.
KEYWORDS: breakfast, circadian, colds, depression, discovery, innovation,
insomnia, obesity, sitting, sugar
http://www.bbsonline.org/Preprints/Roberts/Referees/
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