We would like to remind you about our next event from the ELTE Cognitive
Seminar series:
*Skyla Herod*
*Behavioral and neuroendocrine profiles of response to early life stress in
serotonin transporter knockout (SERT-KO) mice*
Place: ELTE-PPK, Institute of Psychology, Izabella utca 46, room P3
Time: April 21st, 2016 (Thursday), 17:00
Summary:
The serotonin transporter gene (Slc6a4) is associated with several
psychiatric and neurodevelopment disorders, including depression, anxiety,
autism, and schizophrenia. In this genetic knockout mouse line, deletion of
the Slc6a4 gene mimics the serotonergic functioning of these clinical
conditions. In this study, we characterize the behavioral profiles of these
mice, that have been exposed to early adolescent stress with and without
maternal presence, in an attempt to describe what happens when genetic and
environmental risk factors for these disorders are compounded.
Corticosterone response to stress as measured in mouse hair is described,
as part of a validation study to measure glucocorticoid levels using this
non-invasive technique in laboratory animals.
Host: dr. Ildikó Király
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