koglist February 2006

koglist@maillist.ttk.hu

20 participants
32 discussions

Extended deadline: ESSLLI Student Session 2006

by Sophia Katrenko

******************************************************************** DEADLINE EXTENSION: FEBRUARY 15 ESSLLI 2006 STUDENT SESSION July 31 – August 11, Málaga, Spain http://www.science.uva.nl/~katrenko/stus06 ******************************************************************** ---- apologies for multiple copies ---- Due to great popularity and many requests for individual extension we have decided to extend the deadline for the Student Session of the 18th European Summer School in Logic, Language and Information (ESSLLI), which will be held July 31 – August 11, in Málaga, Spain. We invite papers for oral and poster presentation from the areas of Logic, Language and Computation. Submissions for poster presentations are specially encouraged. Student authors, undergraduates as well as graduates, are invited to anonymously submit a full paper, no longer than 7 pages (including references). Papers should be submitted with clear indication of the selected modality of presentation, i.e. oral or poster. Accepted papers will be published in the Student Session Proceedings. The preferred format of submission is PDF. All submissions must be accompanied by a plain text identification page, and be submitted online via http://www.easychair.org/StuSESSLLI2006/. Please visit our website at http://www.science.uva.nl/~katrenko/stus06 for more information about the technical details concerning submission. If you have any questions, you may contact the chairs Janneke Huitink and Sophia Katrenko at esslli(a)science.uva.nl. Important Dates: Extended Deadline: February 15, 2006 Notification of authors: April 1st, 2006 ESSLLI: July 31 – August 11, 2006 -- Sophia Katrenko Human Computer Studies Laboratory Informatics Institute Faculty of Science Universiteit van Amsterdam Kruislaan 419, Matrix I 1098 VA Amsterdam The Netherlands Tel.: +31 20 888 4686 http://staff.science.uva.nl/~katrenko/

20 years, 3 months

Keller & Miller/Evolutionary genetics of mental disorders: BBS Call for Commentators

by Behavioral & Brain Sciences

Dear Dr. Qwerty, ================================================================== *** IMPORTANT INSTRUCTIONS *** ================================================================== Please DO NOT respond to this email. If you wish to submit a proposal for commentary and/or suggest potential commentators, please go to the new Online Commentary Proposal System at the following URL: http://www.bbsonline.org/perl/commentary/commproposal?authordir=Keller-1011… * If you only wish to suggest potential commentators, please ignore prompts to submit a proposal with expertise information. * If you experience technical difficulties, please email bbs(a)bbsonline.org. NOTE: Commentators must be BBS Associates, or suggested by a BBS Associate. If you are not a BBS Associate, please follow the instructions linked below: http://www.bbsonline.org/Instructions/associnst.html ** Please respond to this Call no later than February 21, 2006 ** ================================================================== CALL FOR COMMENTATORS ================================================================== Below is a link to the forthcoming BBS target article "Resolving the paradox of common, harmful, heritable mental disorders: Which evolutionarygenetic models work best?" by Matthew C. Keller and Geoffrey Miller This article has been accepted for publication in Behavioral and Brain Sciences (BBS), an international, interdisciplinary journal providing Open Peer Commentary on important and controversial current research in the biobehavioral and cognitive sciences. The Calls are sent to 10,000 BBS Associates, so there is no expectation (indeed, it would be calamitous) that each recipient should comment on every occasion! Please DO NOT prepare a commentary unless you eventually receive a formal invitation, indicating that it was possible to include your name on the final list, which is constructed so as to balance areas of expertise and frequency of prior commentaries in BBS. To help you decide whether you would be an appropriate commentator for this article, an electronic draft is retrievable at the URL that follows the abstract and keywords below. ======================================================================= *** TARGET ARTICLE INFORMATION *** ======================================================================= TITLE: Resolving the paradox of common, harmful, heritable mental disorders: Which evolutionary genetic models work best? AUTHORS: Matthew C. Keller and Geoffrey Miller ABSTRACT: Given that natural selection is so powerful at optimizing complex adaptations, why does it seem unable to eliminate genes (susceptibility alleles) that predispose to common, harmful, heritable mental disorders, such as schizophrenia or bipolar disorder? We assess three leading explanations for this apparent paradox from evolutionary genetic theory: ancestral neutrality (susceptibility alleles were not harmful among ancestors), balancing selection (susceptibility alleles sometimes increased fitness), and polygenic mutation-selection balance (mental disorders reflect the inevitable mutational load on the thousands of genes underlying human behavior). The first two explanations are commonly assumed in psychiatric genetics and Darwinian psychiatry, while mutation-selection has often been discounted. All three models can explain persistent genetic variance in some traits under some conditions, but the first two have serious problems in explaining human mental disorders. Ancestral neutrality fails to explain low mental disorder frequencies and requires implausibly small selection coefficients against mental disorders given the data on the reproductive costs of mental disorders. Balancing selection (including spatio-temporal variation in selection, heterozygote advantage, antagonistic pleiotropy, and frequency-dependent selection) tends to favor environmentally contingent adaptations (which would show no heritability) or high-frequency alleles (which psychiatric genetics would have already found). Only polygenic mutation-selection balance seems consistent with the data on mental disorder prevalence rates, fitness costs, the likely rarity of susceptibility alleles, and the increased risks of mental disorders with brain trauma, inbreeding, and paternal age. This evolutionary-genetic framework for mental disorders has wide-ranging implications for psychology, psychiatry, behavior genetics, molecular genetics, and evolutionary approaches to studying human behavior. KEYWORDS: adaptation, behavior genetics, Darwinian psychiatry, evolution, evolutionary genetics, evolutionary psychology, mental disorders, mutation-selection balance, psychiatric genetics, quantitative trait loci (QTL). FULL TEXT: http://www.bbsonline.org/Preprints/Keller-10112005/Referees/ ================================================================== *** IMPORTANT INSTRUCTIONS *** ================================================================== Please DO NOT respond to this email. If you wish to submit a proposal for commentary and/or suggest potential commentators, please go to the new Online Commentary Proposal System at the following URL: http://www.bbsonline.org/perl/commentary/commproposal?authordir=Keller-1011… * If you only wish to suggest potential commentators, please ignore prompts to submit a proposal with expertise information. * If you experience technical difficulties, please email bbs(a)bbsonline.org. NOTE: Commentators must be BBS Associates, or suggested by a BBS Associate. If you are not a BBS Associate, please follow the instructions linked below: http://www.bbsonline.org/Instructions/associnst.html ** Please respond to this Call no later than February 21, 2006 ** ================================================================== ================================================================== Barbara Finlay - Editor Paul Bloom - Editor Behavioral and Brain Sciences bbs(a)bbsonline.org http://www.bbsonline.org -------------------------------------------------------------------

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koglist February 2006