Dear All, this is a kind reminder of:
The CEU Department of Cognitive Science and the Center for Cognitive Computation cordially invites you to the following talk by:
Tobias H. Donner, Dept. of Neurophysiology & Pathophysiology, University Medical Center Hamburg-Eppendorf
Date: Wednesday, June 12, 2024
Time: 4 pm (to 5:30 pm) CET
Venue: D001
(QS Vienna)
Zoom: https://ceu-edu.zoom.us/j/94220985433?pwd=SUlzZk0yRTVNYmdsTm5pWUd5VDFYUT09
Meeting ID: 942 2098 5433, Passcode: 852960
Chair: Jozsef Fiser
Flexible Behavior through Adaptive Brain Network Dynamics
Cognitive behavior rapidly adapts to changing environmental contexts. This flexibility distinguishes cognitive behavior from reflexes. I propose that this flexibility results from the rapid reconfiguration of distributed cortical networks that implement
the transformations required by a given task and context. This reconfiguration is enabled by rapid plasticity mechanisms that are controlled by neuromodulators released from the brainstem. To support these claims, I will present human MEG and fMRI experiments,
in which we systematically manipulate context variables, such as task rules or environmental volatility. We quantify the resulting changes in content-specific neural interactions (e.g., selective for sensory evidence or behavioral choice), across a large set
of cortical regions. We relate these cortical interactions to the dynamics of (proxies of) brainstem modulatory activity. This approach reveals that the structure of cortical interactions changes in a context-dependent manner. These changes are predicted by
brainstem modulatory activity, which, in turn, tracks hidden changes in the environment. Preliminary results indicate that the cognitive recruitment of modulatory brainstem systems is impaired in individuals with a high risk of developing psychosis. Our results
open a new window on the dynamic brainstem sculpting of large-scale cortical networks for flexible cognitive behavior. I speculate that this sculpting goes awry in many mental disorders.
*Anyone not affiliated with CEU wishing to attend in-person in Vienna
must reply here to get access to the lecture hall.
Let
Jozsef know, please, if you would like to schedule a meeting with the speaker.
organized by The Department of CogNitive SCience and
the CENTER FOR COGNITIVE COMPUTATION
Best,
Reka
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GyörgyNÉ Finta (Réka)
Department Coordinator
Department of cognitive SCience
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